At Metagenics, we’re always striving to bring you the most effective, science-backed natural health solutions. That’s why we’re excited to introduce MagActive®, our next-generation magnesium that’s up to 4 times better absorbed than common forms of magnesium like magnesium oxide*.
Why Magnesium Matters
Magnesium is essential for over 600 biochemical reactions in the body. It supports everything from muscle relaxation and energy production to stress resilience and nervous system health. But not all magnesium supplements are created equal many are poorly absorbed or can cause digestive discomfort.
What Makes MagActive® Different?
MagActive® is a high-potency magnesium bisglycinate that’s been carefully developed to deliver superior absorption and gentle digestive tolerance. Here’s what sets it apart:
- Up to 4x better absorbed than magnesium oxide*
- Gentle on the stomach, even at higher doses+
- Clinically relevant strength to support whole-body magnesium balance
- Feel a difference in as little as 3 days†
This means more magnesium gets where it’s needed your cells so you can feel the benefits faster.

The Science Behind the Absorption
MagActive® is fully chelated, meaning the magnesium is bound to glycine, a naturally occurring amino acid. This structure helps protect the magnesium from binding with other compounds in the gut that can block absorption. It also allows it to be absorbed through multiple pathways in the digestive tract, making it more efficient and effective.
In fact, in a simulated digestive model, MagActive® showed over 60% absorption, outperforming other forms of magnesium including citrate, glycerophosphate, and oxide.*
Supporting Stress and Muscle Relaxation
Did you know that stress can deplete your magnesium levels? And that low magnesium can make it harder to cope with stress? It’s a vicious cycle. MagActive® helps break that cycle by supporting healthy magnesium levels and promoting muscle relaxation thanks in part to its ability to increase nitric oxide (NO) production in muscle cells, a natural muscle relaxant.
Now Available in MetaRelax® Daily Tablets
You can now experience the benefits of MagActive® in our new MetaRelax® Daily Tablets a fast-acting, well-absorbed magnesium supplement designed to support mind and body relaxation. This convenient tablet format starts working in just 30 minutes, making it easy to incorporate into your daily routine.
Formulated with MagActive® magnesium bisglycinate and a blend of B vitamins, MetaRelax® Daily is ideal for those looking to support stress resilience, muscle relaxation, and overall wellbeing.
Ready to Feel the Difference?
Whether you're managing stress, supporting muscle recovery, or just looking to maintain your magnesium levels, MagActive® is here to help you feel your best faster.
Disclaimers
*Up to 4x better absorbed compared to magnesium oxide. Vynckier et al, J of Nutr & Food Sci. 2020. Sponsored by Metagenics Inc., Europe.
+Compared to magnesium chloride and oxide.
†Based on formulations providing ≥200 mg magnesium per day.
Frequently Asked Questions
1. What is MagActive®?
MagActive® is Metagenics’ next-generation magnesium bisglycinate, scientifically developed for superior absorption and gentle digestive tolerance. It’s up to 4x better absorbed than common forms like magnesium oxide.*
2. What makes MagActive® different from other magnesium forms?
Unlike standard magnesium supplements, MagActive® is fully chelated, meaning the magnesium is bound to glycine. This structure:
- Protects magnesium from binding with dietary anti-nutrients
- Enhances absorption through multiple pathways in the gut
- Supports both active and passive transport channels
3. What are the benefits of better absorption?
Better absorption means more magnesium reaches your cells, where it helps:
- Relax muscles
- Support energy production
- Improve stress resilience
- Maintain nervous system health
You may feel a difference in as little as 3 days†.
4. Is MagActive® gentle on the stomach?
Yes! MagActive® is designed to be gentle on the gut, making it ideal for those who experience digestive discomfort with other magnesium forms.+
5. Does MagActive® support stress and relaxation?
Yes. MagActive® has been shown to increase nitric oxide (NO) synthesis in muscle cells, promoting natural muscle relaxation. This helps support the body’s stress response from the bottom up.
6. Is MagActive® suitable for daily use?
Absolutely. MagActive® is featured in Metagenics products like MetaRelax® Daily Tablets, designed for everyday support of stress, sleep, and mood.